Methyl 3-O-methylgallate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

3-O-甲基没食子酸甲酯是一种罕见的天然产物，具有良好的抗氧化活性。

Methyl 3-O-methylgallate is a rare natural product that showed promising antioxidant activities.(In Vitro):Methyl 3-O-methylgallate showed antioxidant activity without prooxidant effect in neuronal SH-SY5Y cells.(In Vivo):Animals were treated with either Methyl 3-O-methylgallate(10 and 20 mg/kg i.p.), vitamin C (10 mg/kg i.p.) as the standard antioxidant or the vehicle (5 % dimethyl sulfoxide; 1 ml/kg) for 1 week. Oxidative stress was induced in the brain by adding 600 ppm NaF in the drinking water for 7 days. At the end of the treatment period, the levels of thiobarbituric acid reactive substances (TBARS), reduced glutathione and the activities of antioxidant enzymes (superoxide dismutase and catalase) were evaluated in brain homogenates. Methyl 3-O-methylgallate mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.

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Methyl 3-O-methylgallate (M3OMG; 10 and 20 mg/kg, i.p., ) treatment mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities. Animal Model:Fifty male Wistar rats (8-12 , 7-days old, 200-250 g).Dosage:10 and 20 mg/kg.Administration:I.P. for 1 week.Result:Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.

M3OMG

Others

Other Targets

chitin synthesis

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3934-86-9

198.174

C9H10O5

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (504.62 mM)

COC(=O)c1cc(O)c(O)c(OC)c1

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(-20℃)

With Ice Pack

≥ 2 years